mcp-gnomad

Broad Institute gnomAD genomic variant database (GraphQL)

Part of Pipeworx — an MCP gateway connecting AI agents to 250+ live data sources.

Tools

Tool	Description
`variant`	Variant by chr-pos-ref-alt (e.g. "1-55051215-G-A") or rsid.
`gene`	Gene info + variants. Accepts gene symbol (e.g. "BRCA1") or Ensembl gene id.
`region`	Variants in a genomic region (≤25kb recommended).
`transcript`	Transcript + variants.
`search`	Gene / variant search (autocomplete).

Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):

{
  "mcpServers": {
    "gnomad": {
      "url": "https://gateway.pipeworx.io/gnomad/mcp"
    }
  }
}

Or connect to the full Pipeworx gateway for access to all 250+ data sources:

{
  "mcpServers": {
    "pipeworx": {
      "url": "https://gateway.pipeworx.io/mcp"
    }
  }
}

Instead of calling tools directly, you can ask questions in plain English:

ask_pipeworx({ question: "your question about Gnomad data" })

The gateway picks the right tool and fills the arguments automatically.

MIT